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By activating GLP-1 receptors in the gut, these medications may help support the intestinal barrier function that is compromised in Hashimoto's patients

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With respect to the applicant's claim that SER-109 may reduce the number of future hospitalizations or physician visits for patients diagnosed with rCDI, the applicant cites the Feurstadt study to suggest that reduced rates of rCDI shown in Phase III clinical trials would likely lead to fewer days in hospital

Berberine has been shown to support healthy glucose and fat metabolism, as well as cardiovascular and GI health.* Barimelts uses Berberine Phytosome, shown to be up to 4x more bioavailable than standard berberine for enhanced absorption

Improved metabolic flexibility: GLP-1RA improves insulin sensitivity, enabling the body to more efficiently utilize fat for energy during fasting and glucose for energy during feeding, thereby enhancing metabolic flexibility and reducing the risk of metabolic disorders